Computational Biologist, Neuroscience
Location
Salt Lake City, Utah
Level
Senior
Department
Computational Biologist
Type
Full - Time
Salary
Job Description
Posted on:
February 13, 2023
In this role, you will be at the forefront of reimagining neuroscience drug discovery using Recursion’s unique capacity to perform >1 million experiments per week. You will be part of multiple computational and/or therapeutics projects from inception to preclinical development, with the ultimate goal of bringing life-changing therapeutics to patients living with neurological or neurodegenerative disease.
Responsibilities
- Integrate and analyze pre-clinical internal and public domain datasets to generate and evaluate hypotheses for new disease indications, drug discovery, biomarker development and mechanism of action
- Accelerate translational neuroscience discovery through your ability to design and productionize analyses, data integration, and data interpretation
- Drive collaborations with internal groups and external partners for target nomination, in-vitro and in-vivo validation, data science, and machine learning
- Work cross-functionally with Recursion’s data science and drug development teams to further advance Recursion’s ability to interpret and translate large-scale phenomics data into therapeutic programs
- Lead drug discovery programs in neuroscience and rare disease
- Use established bioinformatic analysis pipelines and propose innovative solutions to integrate and interpret -omics data types including genomics, transcriptomics, single cell sequencing, proteomics, and metabolomics using appropriate computational and statistical methods
- Create visualizations, interpret high dimensional data, and explain results to cross-functional teams
- Work collaboratively with data scientists and data engineering groups to enhance our computational infrastructure, user interface, query, and visualization capabilities
- Present data effectively to participants across levels and functional groups in the organization
- Iterate quickly to move from ideation to validation on multiple projects at an accelerated pace
Job Requirements
- PhD in a relevant field (neuroscience, bioinformatics, statistics) or MS in a relevant field and 2+ years of experience.
- Demonstrated experience mining and integrating large multimodal data sets (including proteomics, transcriptomics, GWAS, genomics; in-house or publicly available) to identify targets and/or pathways relevant to drug discovery. Industry drug discovery experience preferred.
- Strong data visualization skills
- Fluency and experience working with high-level programming language such as Python or R for complex data analysis
- Experience leading drug discovery teams and efficiently advancing projects through proof of concept to preclinical
- Understanding of current state of therapeutic development and ability to drive scientific strategy
- Demonstrated ability to carry and prioritize among multiple projects
