Freenome

Staff Machine Learning Scientist

Job Description

Posted on: 
November 8, 2023

The ideal candidate has a strong knowledge of machine learning (ML) fundamentals and deep learning (DL) methods, a track record of successfully answering complex research questions, and the ability to thrive in a highly cross-functional environment.

They will be responsible for the development of algorithms for early, noninvasive detection tests for multiple cancers. They will build on a foundation of ML/DL and statistical skills to develop models for multiomic molecular signals from blood. They will also work with computational biologists, molecular biologists and ML engineers to drive research experiments and become the primary drivers towards Freenome’s mission of solving cancer.

Responsibilities

  • Independently pursue cutting edge research in artificial intelligence applied to biological problems (including cancer research, genomics, computational biology/bioinformatics, immunology and more)
  • Pursue research projects that identify new methods for modeling various biological changes resulting from disease
  • Build models that achieve high accuracy, and apply contemporary interpretability techniques to provide a deeper understanding of the underlying signal and biological mechanisms
  • Interface with product teams to identify potential new problem areas that can benefit from state of the art ML/DL methods.
  • Work closely with ML Engineering partners to ensure that Freenome’s computational infrastructure supports optimal model training and iteration
  • Take a mindful, transparent, and humane approach to your work

Job Requirements

  • PhD or equivalent research experience with an AI or ML emphasis and in a relevant, quantitative field such as Computer Science , Statistics, Mathematics, Engineering, Computational Biology, or Bioinformatics
  • 6+ years of post-PhD industry experience working on the technical subject matter
  • Expertise, demonstrated by research publications or industry achievements, in applied machine learning, deep learning and complex data modeling
  • Practical and theoretical understanding of fundamental ML models like generalized linear models, kernel machines, decision trees, neural networks; boosting and model aggregation; Bayesian inference and model selection; and variational inference
  • Practical and theoretical understanding of DL models like large language models, foundation models, and training paradigms like contrastive learning and self-supervised learning
  • Proficient in current state of the art in ML/DL approaches in different domains, with an ability to envision their applications in biological data
  • Proficiency in a general-purpose programming language: Python, R, Java, C, C++, etc.
  • Proficiency in one or more ML frameworks: Pytorch, Tensorflow, Jax, etc.
  • Excellent ability to communicate across disciplines and work collaboratively towards next steps in experimental iterations
  • Proficient at productive cross-functional scientific communication and collaboration with software engineers and computational biologists
  • A passion for innovation and demonstrated initiative in tackling new areas of research

Nice to haves:

  • Deep domain-specific experience in computational biology, genomics, proteomics or a related field
  • Experience in NGS data analysis and bioinformatic pipelines
  • Experience with containerized cloud computing environments, such as Docker in GCP or AWS
  • Experience in a production software engineering environment, including the use of automated regression testing, version control, and deployment systems

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